Streptomyces, metabolic potential

The antibiotic prumycin, a metabolic of Streptomyces strain No. F-1028, is also a potential fungicide, its main range of action involving Botrytis, Sclerotinia and Sphaerotheca spp. It is not toxic to mammals (Hata et al., 1971). The structure of prumycin has been determined by Omura et al. (1972) to be a 2,5-diamino-2,5-dideoxypentose-5D-alanyl derivative (20). 

Prokaryotes have seldom been considered as potential sources of antimutagens, although the similarity of basic metabolic reactions in pro-and eukaryotes, on the one hand, and the ability of prokaryotes to carry out some unique reactions, on the other, do not exclude bacteria as possible sources of new and valuable antimutagens (anticarcinogens). This suggestion is supported by the results of investigations in Streptomyces (Osawa et al,... 

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