Streptomyces ikutamanensis

FIGURE 19.88 Metabolic pathways of (+)-cw-carveol (81b) by Streptomyces bottropensis SY-2-1 and Streptomyces ikutamanensis Ya-2-1. (Modi ed from Noma, Y. and Nishimura, H., Agric. Biol. Chem., 51, 1845, 1987 Nishimura, H. and Noma, Y, Biotechnology for Improved Foods and Flavors, G.R. Takeoka et al., ACS Symp. Ser. 637, pp. 173-187. American Chemical Society, Washington, DC, 1996.)... 

FIGURE 19.116 Substrates used for the hydrogenation of C = C double bond with Pseudomonas ovalis strain 6-1, Streptomyces bottropensis SY-2-1, Streptomyces ikutamanensis Ya-2-1, and Euglena gracilis Z. 

Nnma Y anri N shimnL Streptomyces ikutamanensis Ya-2-1. (Modi ed from... 

Noma, Y M. Miyazawa, K. Yamamoto, H. Kameoka, T. Inagaki, and H. Sakai, 1984. Microbiological conversion of perillaldehyde. Biotransformation of I- and d/-perillaldehyde by Streptomyces ikutamanensis, Ya-2-1, Proceedings of the 28th TEAC, pp. 174-176. 

FIGURE 14,9 Reduction of terpene aldehydes and epoxidation of terpene alcohols by Streptomyces ikutamanensis, Ya-2-1. (Modified from Noma, Y. et al., 1986. Proc. 30th TEAC, pp. 204-206.)... 

Cumin aldehyde (193) is transformed by Euglena (Noma et al., 1991a), Dunaliella (Noma et al., 1991b), and Streptomyces ikutamanensis (Noma et al., 1986) to give cumin alcohol (192) as the major product and cuminic acid (194) as the minor product (Figure 14.60). 

Perillyl alcohol (74 ) was epoxidized by Streptomyces ikutamanensis Ya-2-1 to give 8,9-epoxy-(-)-perillyl alcohol (77 ) (Noma et al., 1986) (Figure 14.100). 

In case of Streptomyces ikutamanensis, Ya-2-11,8-cineole (122) was biotransformed regioselec-tively to give (-i-)-3a-hydroxy-l,8-cineole (123b, 46%) and (-f-)-3 i-hydroxy-l,8-cmeole (123b, 29%) as the major product. Recovery ratio as ether extract was ca. 8.5% in Streptomyces ikutamanensis, Ya-2-1 (Noma and Nishimura, 1980, 1981) (Figure 14.135). 

FICU RE 14.136 Biotransformation of 1,8-cineole (122), (+)-3a-hydroxy-l,8-cineole (123b), (+)-3p-hydroxy-l,8-cineole(123a), and (+)-3-oxo-l,8-cineole (126a) by Streptomyces ikutamanensis, Ya-2-1. (Modified from Noma, Y. and H. Nishimura, 1981. Annual Meeting of Agricultural and Biological Chemical Society, Book of abstracts, p. 196.)... 

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