Strempeliopsis strempelioides

The first extractions of Strempeliopsis strempelioides K. Schum. (Family Apo-cynaceae), from Cuba, reveal that it is rich in alkaloids. The leaves and stem bark contain, amongst others, (+)-tubotaiwine and (+)-condylocarpine, and the stem bark also contains (-)-apparicine.80 Apparicine (pericalline) also occurs, together with O-acetylvallesamine, 19,20-dihydrocondylocarpine, and eleven other alkaloids, in the wood and stem bark of Ervatamia heyneana (Wall.) T. Cooke,81 and... 

The indolenine (232) has been neatly used in a synthesis of ( )-strempeliopine (233), the laevorotatory enantiomer of which has recently been isolated from Strempeliopsis strempelioides K.. Schurn.108 Reductive rearrangement of (232) by... 

Strempeliopidine (626) was obtained from Strempeliopsis strempelioides, a plant indigenous to Cuba (387). Acid hydrolysis gave aspidospermidine (627), while reductive cleavage (Sn/HCl) yielded dihydroeburnamenine, from which it was deduced that strempeliopidine was constituted from the union of aspidospermidine and eburnane moieties. This was supported by partial synthesis through acid-induced condensation of eburnamine (not stated which enantiomer was used) with aspidospermidine. Since... 

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