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Strategies for Signal Amplification

Andras SC, Power JB, Cocking EC, and Davey MR (2001) Strategies for signal amplification in nucleic acid detection. Molecular Biotechnology 19 29—44. [Pg.106]

A number of additional strategies for signal amplification in ELISAs have been developed. One example is the use of secondary antibodies conjugated to biotin, a molecule that has very strong affinity (>10 1 mol ) for the egg yolk protein avidin. After application of the secondary antibodies and washing to remove unbound reagents, the substrate is flooded with an excess of enzyme-conjugated avidin. Not only is the interaction between avidin and biotin... [Pg.2123]

MR contrast agents based on host-guest inclusion between cyclodextrin and small-molecule Gd " " complexes have been synthesized in the past few years as a strategy for signal amplification and accumulating... [Pg.3371]

Hong C, Yuan R, Chai Y, Zhuo Y, Yang X (2012) A strategy for signal amplification using an amperometric enzyme immunosensor based on HRP modified platinum nanoparticles. J Electroanal Chem 664 20-25... [Pg.566]

Chen B-X, Szabolcs MJ, Matsushima AY, et al. A strategy for immunohistochemical signal enhancement by end-product amplification. J Histochem Cytochem. 1996 44 819. [Pg.38]

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Signal amplification

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