Sterilization schematic drawing

Fig. 2.43. Schema of a steam-sterilizable closing mechanism for vials. The pressure plate (1), by which the stoppers are pushed into the vials is sterilized jointly with the chamber. The shaft (2) to which the pressure plate is connected, moves into the chamber during stoppering. It is not sterilized with the chamber. Therefore the shaft is sterilized in a separate chamber (3). This chamber can also be connected to the vacuum pumping system (4) as to the steam supply (5). Water condensing during the sterilization can be drained by (6). A special seal (7) can (by (8)) also be connected to steam or vacuum, and be sterilized (schematic drawing from information by AMSCO Finn-Aqua, D-50354 Hiirth).

Figure 5.1 Steam sterilizer. Schematic drawing showing typical components.

Brief description of ventilation systems. More details should be given for critical areas with potential risks of airborne contamination (schematic drawings of the systems are desirable). Classification of the rooms used for the manufacture of sterile products should be mentioned. 

Figure 22-5. Schematics of BIOPEM (B. Braun Melsungen), a magnetically stirred filtration cell for continuous sampling under sterile conditions, a) whole module b) schematic drawing with adjustable stirrer assembly. (1 top plate 2 adjustable magnetic stirrer assembly 3 bottom plate 4 channels S shut-off valve 6 outlet line 7 inlet line) (reproduced by permission of B. Braun Melsungen, Germany).

---