Sterilization drug stability problems

The following conclusions can be offered at the end of this brief review. Emulsion systems, particularly, mtcroemulsions, seem to be developing rapidly toward commercial applications and possibly will become the vehicles of choice for lipid-soluble ophthalmic drugs. Traditional suspensions, used for ocular administration of drugs both water- and lipid-insoluble, after some initial uncertainties have apparently reached a stale of technical perfection. However, both emulsions and suspensions are not exempt of drawbacks and problems such as stability, sterilization, bioavailability. etc., which may limit their practical usefulness. 

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