Stereospecific a-glycosylation

The remarkable feature of this approach is that it could be utilized towards direct, stereospecific a-glycosylation. This was illustrated by addition of sugar alcohols to ketene dithioacetals, promoted by TMSOTf, to reach after oxidative hydrolysis of the dithianyl residue, the corresponding a-disaccharides in high yield [130a], The steric course of the glycosylation reaction, is possibly controlled by the influence of the dithianyl group for the attack of a nucleophile on one side. 

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See also in sourсe #XX -- [ , ]

See also in sourсe #XX -- [ ]

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