Stereoselectivity of Hydrolases

The enantioselectivity that the enzymes display is not always very large. Indeed, there are even examples known for the opposite selectivity. Nonetheless, with these general rules, it is possible to address a large number of synthetic problems. For the detailed choice of the right biocatalyst for each particular substrate, several excellent reviews are available [2, 16-23]. 

For the other hydrolases general rules for their enantioselectivity are not available. This does not mean that their enantioselectivities are unknown indeed for many enzymes much knowledge is available, however, less is known about the entire class of enzymes of which these individual, well-researched enzymes are an element. 

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