Stereodivergent process

Stereodivergent process for synthesis of the decahydroquinoline type of Dendrobates alkaloids... 

Toyooka, N., Okumura, M., Nemoto, H. Stereodivergent process for the synthesis of the decahydroquinoiine type of dendrobatid aikaioids. J. Org. Chem. 2002, 67, 6078-6081. 

Starting from achiral reactants, dual and highly enantloselective catalyst system can govern the overall stereodivergent process. Ingenious examples in the field of organocatalysis have been reported (53). For instance, the combination of catalyst 26 and homochiral proline (Fig. 6) led to an optically pure diastereomeric product, either 27 and 28, depending upon whether L or D proline was used (54). 

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