Steps Required Before Implementation

Human Health and the Environment, 96 Environmental Compliance and Monitoring, 97 Assessment of Overarching Technical Issues, 97 Steps Required Before Implementation, 97 Findings and Recommendations, 97 Findings, 97 Recommendations, 98... 

ASSESSMENT OF OVERARCHING TECHNICAL ISSUES Steps Required Before Implementation... 

By common agreement, at the ICH SC meeting, all three parties would accept applications in the CTD format from 1 July 2001. This would be on a so-called voluntary basis, as the time required before implementation could become mandatory and vary according to the formal steps needed in the three regions. It was apparent that a question in the minds of many in the audience was whether the new format would really replace current requirements. At several points in the CTD, there is provision for authorities to ask for additional information according to regional requirements. ... 

BEM. This in part has been due to the perceived difficulty [6] of implementation with some relatively involved mathematical steps required before numerical solution. In addition, the application of the method to problems of complex chemical reactivity is challenging. However, the method does possess some benefits over both the EEM and EDM. In particular. 

The next step in the process involves the implementation of the automated synthesis and generation of the library. Significant lead time is anticipated before a library can be produced because even the most reliable chemical reactions require optimization if they are to be carried out by a robot, particularly if... 

Successful development and implementation of various chemical sensors for ocean measurements (based on optical, electrochemical, or mass transducers) requires concomitant advances in the design or discovery of organic or inorganic molecules that interact selectively with the important ocean analytes. These developments are particularly important for in situ sensors where no separation of ocean components or addition of external reagents occurs before or during the measurement step. 

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