Big Chemical Encyclopedia

Chemical substances, components, reactions, process design ...

Articles Figures Tables About

Stephens-Castro coupling copper acetylide intermediates

Copper acetylides of protected propargyl alcohols have been used as partners in Castro-Stephens couplings on multiple occasions. Coupling of iodopyrimidine 44 with the pre-formed copper reagent 45 was carried out in refluxing pyridine was complete in 2.5 hours, and gave the desired pyrimidine 46 in high yield. This intermediate was used to synthesize uracils with novel carbon substituents. ... [Pg.224]

See other pages where Stephens-Castro coupling copper acetylide intermediates is mentioned: [Pg.217]    [Pg.219]    [Pg.102]    [Pg.214]    [Pg.218]    [Pg.218]    [Pg.223]    [Pg.227]    [Pg.226]   
See also in sourсe #XX -- [ Pg.3 , Pg.217 ]

See also in sourсe #XX -- [ Pg.217 ]

See also in sourсe #XX -- [ Pg.3 , Pg.217 ]



SEARCH



Acetylide

Acetylides

Castro

Castro coupling

Copper acetylides

Copper couples

Coupling intermediate

Stephen

Stephens-Castro coupling

© 2024 chempedia.info