Stannylpyrrole aldehyde

Dubac has employed a Stille coupling reaction to synthesize the pyrroles 88 and 89 from stannylpyrrole aldehyde 87 [71]. The latter tin compound was prepared as shown, and related stannylpyrroles were synthesized similarly [72] or using Muchowski s 6-dimethylamino-l-azafulvene dimer lithiation methodology [73]. 

The stannylpyrrole aldehyde shown below underwent the Stille coupling with the aldehyde group unmolested. The Stille coupling between stannylpyrrole aldehyde and acid chloride was used to synthesize the sponge metabolite mycalazol 11 and related compounds, which have activity against the P388 murine leukemia cell line. ... 

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See also in sourсe #XX -- [ ]

See also in sourсe #XX -- [ ]

See also in sourсe #XX -- [ ]

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