Stannyl ethers nucleosides

Transmetallation can be employed in order to avoid the use of strongly basic conditions. One such variant is the [2,3]-Wittig-Still rearrangement wherein stannyl ethers can be converted to homoallylic alcohols. Several examples of this tranformation in the synthesis of amino acid components of bioactive polyoxins have been reported by Ghosh. In their synthesis of 5-0-carbomylpolyoxamic acid, a bioactive amino acid nucleoside, E and Z-allylic stannyl ethers, such as 45, derived from an isopropylidene L-threitol derivative, were subjected to the [2,3]-Wittig-Still rearrangement. 

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See also in sourсe #XX -- [ ]

See also in sourсe #XX -- [ ]

See also in sourсe #XX -- [ ]

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