Stability graphical conventions

Therefore, data on the variation of log D with HA, pH at a constant H3Cit concentration and on log D versus cit at constant pH, allows the determination of the stability constants of these complexes by conventional graphic or computer methods. 

Dyrssen and Sill6n [68] pointed ont that distribntion ratios obtained by conventional batchwise techniques are often too scattered to allow the determination of as many parameters as used in Examples 15 and 16. They suggested a simplified graphic treatment of the data, based on the assnmption that there is a constant ratio between successive stability constants, i.e., KJK i = 10 , and that all distribntion cnrves can be normalized so that A log Pn = where N is the number of ligands A in the extracted complex. Thns, the distribution curve log Du vs. log[A ] is described by the two parameters a and b, and the distribution constant of the complex, Tdc- The principle can be nsefnl for estimations when there is insnfficient reliable experimental data. 

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