Spiroannulation, strain energy

TABLE 1. Calculated (MM2) and experimental heats of formation and strain energy in some spiroannulated cyclopropanes... 

Compound A//r(kcalmol ) MM2 A/7r(kcalmol ) exptl Strain energy (kcalmoL1) Strain energy of spiroannulation (kcalmoL1)... 

It was demonstrated in Section 3 that spiroannulation of cyclopropane to four- and higher-membered rings does not cause an increase in the strain energy of the molecule. It is not surprising, then, that the chemistry of these compounds does not differ from that of simple alkyl substituted cyclopropanes. Since exciting reviews on the chemistry of cyclopropanes are available42, the authors of this chapter will limit the description of properties of SPC of these types to some of their interesting applications. 

A/ff(kcalmol ) A/ff(kcalmol ) Strain energy Strain energy of MM2 exptl (kcalmol ) spiroannulation... 

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