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Spiegelmer Technology

Fig. 3.4.2. Schematic representation of spiegelmer technology. A library of 1015 different oligonucleotides is synthesized and incubated with the mirror-image (or enantiomeric) form of a naturally occurring target. After several cycles of selection and amplification the enriched library is cloned in an appropriate vector and sequenced. Individualized binding oligonucleotides are further... Fig. 3.4.2. Schematic representation of spiegelmer technology. A library of 1015 different oligonucleotides is synthesized and incubated with the mirror-image (or enantiomeric) form of a naturally occurring target. After several cycles of selection and amplification the enriched library is cloned in an appropriate vector and sequenced. Individualized binding oligonucleotides are further...
See other pages where Spiegelmer Technology is mentioned: [Pg.250]    [Pg.252]    [Pg.259]    [Pg.40]    [Pg.45]    [Pg.250]    [Pg.252]    [Pg.259]    [Pg.40]    [Pg.45]    [Pg.180]    [Pg.1]    [Pg.81]   


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Spiegelmers

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