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Spermatid selenoprotein

Spermatid selenoprotein 34 kDa In sperm nuclei and in stomach has GPx activity... [Pg.326]

Selenium plays a special role in development and protection of spermatozoa (Chapter 15). Tire selenoprotein phospholipid hydroperoxide glutathione peroxidase (PHGPx Eq. 15-58, Table 15-4) has a high activity in the testis and in spermatids. However, in mature spermatozoa it forms an enzymatically inactive oxidatively crosslinked capsular material around the midpiece of the cell perhaps providing mechanical stability.268 A similar 34-kDa selenoprotein is present in sperm nuclei and may be essential for condensation of DNA.269 Sperm tails contain specialized cytoskele-tal proteins which form "outer dense fibers."270 In contrast to mammalian spermatozoa, nematode sperm move by ameboid motility that depends upon a specialized actin-like molecule.271 Sperm cells are unusually rich in polyamines, most of which are bound to RNA and DNA (Chapter 24). [Pg.1894]


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