Specific Binding of Alkylglycoside-derivatized AVP in Kidney Plasma Membranes

4 Specific Binding of Alkylglycoside-derivatized AVP in Kidney Plasma Membranes 

Possible explanations for a blood flow-limited uptake in kidney include the existence of specific uptake mechanisms, such as receptor-mediated endocytosis and carrier-mediated transport. Since the former mechanism is initiated by binding of the ligand to the cell-surface receptor, the specific binding of alkylglycoside compounds to isolated tubular plasma membranes was examined [23,24]. 

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