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Sparteine hydroxylase

Cytochrome P450 2D6, also termed debrisoquine-sparteine hydroxylase, is a mixed-function oxidase localized in the endoplasmic reticulum which is responsible for the biotransformation of several tricyclic antidepressants, antipsychotics, beta-blockers, opioids, and many other drugs. [Pg.408]

Table 3 Some Drugs Whose Metabolism Is Catalyzed by the CYP2D6 Enzyme, i.e., the Debrisoquine/Sparteine Hydroxylase... Table 3 Some Drugs Whose Metabolism Is Catalyzed by the CYP2D6 Enzyme, i.e., the Debrisoquine/Sparteine Hydroxylase...
CYP2D6. CYP2D6, also knovm as debrisoquine/sparteine hydroxylase, is highly polymorphic and is inactive in about 8% of Caucasian-Americans and 2-5% of African... [Pg.627]

See other pages where Sparteine hydroxylase is mentioned: [Pg.90]    [Pg.193]   
See also in sourсe #XX -- [ Pg.4 , Pg.627 ]

See also in sourсe #XX -- [ Pg.627 ]



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Sparteines

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