Sophora tomentosa 5-

Epilamprolobine (54) Sophora tomentosa 21), S. chrysophyUa Seem. 107) C15H24N2O2 101.5... 

Af-Acetylcytisine (78) Sophora tomentosa (122), Thermopsis alterniflora Rgl. et Schmalh. (132) C13H16N2O2 210-213... 

PentaOH LAVANDULYL- FLAVANONES 6-Ger-8-Pr C30H36O7 508 Tomentosanol E (Figure 15.3) Sophora tomentosa Leguminosae Root 111... 

Tanaka, T. et al., Flavonoids from the root and stem of Sophora tomentosa. Phytochemistry, 46, 1431, 1997. 

Plugge, P. C. 1891. Das alkaloid von Sophora tomentosa L. Arch. Pharm. 229 561-565. Zhu, J. S., G. M. Halpem, and K. Jones. 1998. The scientific rediscovery of an ancient Chinese herbal medicine Part I. Cordyceps sinensis. J. Alternative and Complementary Med. 4 289-305. 

If the precursor dienes have vinyl end-groups, ethene is eliminated in the metathesis reaction, but it is sometimes advantageous to use a precursor with one or two propenyl end-groups, eliminating propene or but-2-ene in the metathesis reaction. An example is shown in equation 31, the final stage in the synthesis of the protected precursor (42) of Sophora compound I, the antifungal phytoalexine isolated from the aerial part of Sophora tomentosa L228. 

Ten prenylflavanones (10, 69-77) including sophoraflavanone G (10), naringenin (69), hesperetin (70), 6-prenylbaringenin (71), sophoraflavanone B (72), sophoraflavanone A (73), sophoraflavanone D (74), euchrestaflavanone A (75), sophoraflavanone H (76), sophoraflavanone I (77) were extracted from Sophora tomentosa L., and Sophora moorcroftiana Benth. ex Baker (Legumi-nosae) (Fig. 15). 

Table 3 Antitumor activity of isoflavones (27, 28) and isoflavanones (17, 86-93) from Sophora tomentosa L., and Sophora moorcroftiana Benth. ex Baker...

Thermopsis species [74] (Fig. 10). The seedlings of Sophora tomentosa and S. flavescens, on the contrary, exhibited the activity of acetyl-CoA (-)-cytisine N-acetyltransferase [75, 76]. These two enzymatic activities are expressed in the course of seedling development of the specific plant species. 

Isol. from aerial parts of Sophora tomentosa. Plates. Mp 235-237°. 

Isol. from aerial parts of Sophora tomentosa. Shows antifungal activity. Needles. Mp 178-180°. [a] —17.3° (EtOH). 

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