Solasodine-based glycoalkaloids

The solasodine-based glycoalkaloids solamargine and solasonine were isolated from ripe fruits of 5. acculeatissimum. The total solasodine content of these fruits was 3.8%.35 The same glycoalkaloids were found in tissue cultures of S. acculeatissimum,36 while solasodine was isolated from tissue cultures of five Solanum... 

Occurrence of Solasodine-based Glycoalkaloids as well as Solanidine-based... 

Rowers and fruits of any of these chemovarieties of S. dulcamara showed exclusively solasodine-based glycoalkaloids, whereas roots contained the additional aglycone tomatidine and/or 15a-hydroxylated congeners of all four aglycones mentioned. Even 15p-hydroxy-soladulcidine and -solasodine were detected (Table 7.3). Two further soladulcidine-based glycoalkaloids, soladulcines A (P-chacotrio-side) and B (P-lycotetraoside), were isolated and structurally elucidated from the aerial parts of this species in Japan (Lee et al. 1994). 

A few data on total glycoalkaloid concentration in ripe fruits are mentioned in the study of Levin et al. in connection with a potential correlation between seed-dispersal and these metabolites S. mammosum L. showed almost 50 times more than S. capsicoides All., S. myriacanthum Dun. a much higher content than S. viarum Dun., and S. acerifolium Humb. Bonpl. a low content . It might be assumed that these alkaloids are also solasodine-based in case of S. myriacanthum as proven for the remaining four species however, this is speculative. 

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