Soft Mist Aerosols

In recent years research has focused on a new method of pharmaceutical aerosol generation that involves passing a solution formulation through a nozzle or series of nozzles to generate a soft mist aerosol as a bolus dose [271], Aerosol generation... 

Pitcairn, G, Reader, S., Pavia, D., and Newman, S. (2005), Deposition of corticosteroid aerosol in the human lung by respimat soft mist inhaler compared to deposition by metered dose inhaler or by turbuhaler dry powder inhaler, J. Aerosol Med., 18, 264-272. 

Pavia, D., and Moonen, D. (1999), Preliminary data from phase II studies with respimat, a propellant-free soft mist inhaler, J. Aerosol Med., 12(Suppl. 1), S33-39. 

Hochrainer, D., Holz, H., Kreher, C., Scaffidi, L., Spallek, M., and Wachtel, H. (2005), Comparison of the aerosol velocity and spray duration of respimat soft mist inhaler and pressurized metered dose inhalers, /. Aerosol Med., 18,273-282. 

Asakura Y, Nishimura N, Maezawa K, Terajima T, Kizu J, Chohnabayashi N. Effect of switching tiotropium HandiHaler to Respimat Soft Mist Inhaler in patients with COPD the difference of adverse events and usability between inhaler devices. J Aerosol Med Pulm Drug Deliv February 2013 26(l) 41-5. 

---