Sodium dodecanesulphonate

Fuerstenau, D. W., and T. Wakamatsu, Effect of pH on the adsorption of sodium dodecanesulphonate at the alumina/water interface , Faraday Disc. Chem. Soc., 59,157-168 (1975). 

Fig. 4.4.13. Separation of two ionic compounds, phenylephrine (1) and lidocaine (2), and one non-ionic compound, betamethasone valerate (3), on a Nucleosil C8 column (0.46 x IS cm). Eluent O.OOS M sodium dodecanesulphonate in methanol/0.01 M phosphate buffer (pH 4.8) (7 3). Reprinted from Ref. 2S.

Rosen et aL [17] developed a variant of this procedure in which a small amount of ethanol was added to the solution. The method had to be calibrated for each individual type of betaine, by titrating pure material and adjusting the volume of ethanol until a result of 100% was obtained. Using 0.001 M sodium dodecanesulphonate as titrant they successfully titrated the two main types, 2-pyridinium fatty acids of different chain lengths, A -dodecyl-A -benzyl-A -methylglycine and nine commercial betaines. 

Sodium 1-dodecanesulphonate [2386-53-0] M 272.4. Twice recrystd from EtOH. 

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