Snake Elaphe obsoleta

Snakes, two species (Elaphe obsoleta, Nerodia taxispilota), Aiken, South Carolina whole animal, 137Cs... 

Shed snake skin has been proposed as a relatively good model for human skin in transdermal permeation studies [66]. Hirvonen et al. [67] compared the transdermal iontophoresis of sotalol and salicylate in shed snake skin, Elaphe obsoleta, and human cadaver skin. They advised that snake skin should be used with caution as a model for human skin because snake skin has anion-selective properties while human skin has cation-selective properties. 

Figure 15.4 Permeability coefficients from shed snake skin plotted as a function of log Ko , Elaphe obsoleta-, 0, Python molurus or reticulatus] o, excluded Elaphe obso-leta for invalid K -k, excluded zwitterion Elaphe obsoleta, it, excluded zwitte-rion Python molurus.

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