Small perturbations cooperative transitions

Further discussions of kinetic investigations into cooperative transitions will be found throughout this volume. The dynamic complexity of cooperative systems call for the application of a wide range of techniques. Observations following small perturbations of binding equilibria (see chapter 6) can yield information about ligand binding to different states as well as about the transition between these states (Kirschner et al, 1966). Flash photolysis techniques (section 8.1) have been used to evaluate the... 

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