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Small molecule-protein interaction chemical biology based

CHEMICAL BIOLOGY BASED ON SMALL MOLECULE-PROTEIN INTERACTION... [Pg.1]

The Chemical Co-evolution Model was based on the assumption that every NP possessed (or had possessed at some stage in evolution) some biological activity that enhanced the fitness of the producer. This assumption is not supported by experimental evidence and the assumption has no theoretical basis. Extensive studies of collections of both synthetic chemicals and NPs have shown that the probability of any one chemical structure possessing potent, specific biological activity is very low. These experimental findings are supported by the current imderstanding of the way in which small molecules interact with proteins to bring about biomolecular activity. [Pg.91]

See other pages where Small molecule-protein interaction chemical biology based is mentioned: [Pg.98]    [Pg.521]    [Pg.4014]    [Pg.341]    [Pg.106]    [Pg.305]    [Pg.404]    [Pg.203]    [Pg.2]    [Pg.384]    [Pg.588]    [Pg.111]    [Pg.408]    [Pg.16]    [Pg.30]    [Pg.189]    [Pg.38]    [Pg.167]    [Pg.399]    [Pg.405]    [Pg.184]    [Pg.692]    [Pg.2074]    [Pg.2076]    [Pg.518]    [Pg.660]    [Pg.194]    [Pg.8]    [Pg.141]    [Pg.249]    [Pg.145]    [Pg.678]    [Pg.19]    [Pg.130]    [Pg.313]    [Pg.325]    [Pg.826]    [Pg.127]    [Pg.236]    [Pg.373]    [Pg.190]    [Pg.70]   
See also in sourсe #XX -- [ Pg.2 , Pg.3 , Pg.4 , Pg.5 , Pg.6 , Pg.7 ]



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Base molecule

Biologic molecules

Chemical interaction

Molecule chemical

Molecule interaction

Molecules biological

Protein chemical

Protein small molecule

Protein small proteins

Protein-based

Protein-small molecule interaction

Proteins biological

Small-molecule interaction

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