Skeletal muscle changes units

The structure of the contractile unit is fundamental to the interpretation of the relationship between muscle length and isometric tension in skeletal muscle. Each sarcomere unit contains bipolar thick filaments with a central bare zone surrounded by pairs of actin filaments of opposite polarity. The actin filaments are anchored at Z-bands that are aligned in parallel. The length-tension behavior of skeletal muscle has been interpreted in terms of changes in the overlap between the thick eind thin filaments as... 

Although it has been clinically available for a number of years, the United States Food and Drug Administration in early 1968 allowed labeling changes for diazepam (XXIV) to allow for new indications of use for the relief of muscle spasm and adjunctive use in convulsive disorders . It was reported that in cats the brain stem reticular system is the major locus of central nervous system depressant action of this centrally acting skeletal muscle relaxant. 

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