Size exclusion chromatography cleaning columns

Clean-up steps such as SPE, liquid adsorption chromatography in columns, size exclusion chromatography, SPME, solvent exchange, reduction of solvent volume... are absolutely necessary when dealing with food samples. Given the complexity of the food samples, as well as the necessity of a number of clean-up steps to purify the extract, the utilization of IS and/or RS, as well as adequate certified materials, becomes an inherent necessity. These clean-up steps have been described in other sections of this book chapter. 

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