Single skeletal rearrangement reaction

Skeletal rearrangement reactions over Pt single crystals have been studied for methyl cyclopentane, 2- and 3-methylpentane350 and for n-hexane.3sl One conclusion351 is that whereas aromatization reactions are very sensitive to surface structure [Pt(l 11)> Pt(100)], isomerization, Cs-cyclization, and hydrogenolysis reactions display little dependence on structure. Temperature and H2 pressure are more important in affecting the selectivity. 

Davis SM, Zaera F, Somorjai GA (1982) Surface structure and temperature dependence of light-alkane skeletal rearrangement reactions catalyzed over platinum single-crystal surfaces. J Am Chem Soc 104 7453... 

S.M. Davis, F. Zaera, and G.A. Somoijai. Surface Structure and Temperature Dependence of n-Hexane Skeletal Rearrangement Reactions Catalyzed over Platinum Single Crystal Surfaces Marked Structure Sensitivity of Aromatization. J. Catal. 85 206 (1984). 

TT-Acidic transition-metal-catalyzed skeletal rearrangement reaction is one of the most attractive transformations for the construction of highly elaborate molecules in a single operation under mild and neutral reaction conditions [1]. A wide variety of transition-metal elements, such as Pd, Ru, Au, Pt, and Cu, have been utilized as TT-electrophilic catalyst to activate carbon-carbon multiple bonds such as... 

In this synthesis, we have witnessed the dramatic productivity of the intramolecular enone-olefin [2+2] photocycloaddition reaction. This single reaction creates three contiguous and fully substituted stereocenters and a strained four-membered ring that eventually provides the driving force for a skeletal rearrangement to give isocomene. 

The skeletal rearrangement of 1,7-enynes is an extension of the cycloisomerization reaction of 1,6-enynes. 1,7-Enynes undergo single cleavage skeletal rearrangement... 

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