Single sample introduction strategies

It should be taken into account, however, that the isotope ratio precision is typically worse than that with pneumatic nebulization as a means of sample introduction. Recently, Aramendia et al. provided a description of strategies to improve the isotope ratio precision attainable with the combination of LA and single-collector ICP-MS [62]. As the use of LA also affects the degree of mass discrimination, matrix-matched standards are required for adequate mass bias correction [63],... 

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