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Single nucleotide polymorphism SNPs drug response

Rapid sequencing and single nucleotide polymorphisms (SNPs) will play a major role in associating sequence variations with heritable clinical phenotypes of drug or xenobiotic response. SNPs occur approximately once every 300-3,000 base pairs if one compares the genomes of two unrelated individuals [13, 14]. Any two individuals thus differ by approximately 1-10 million base pairs, i.e., in < 1% of the approximately 3.2 billion base pairs of the haploid genome (23 chromosomes). [Pg.5]


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See also in sourсe #XX -- [ Pg.610 ]




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Nucleotide polymorphism

Polymorphic drugs

Single nucleotide polymorphisms

Single nucleotide polymorphisms SNPs)

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