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Single nucleotide polymorphism differential expression

In Chap. 10, McFarlane et al. utilize liquid chromatography (LC)-MS to generate intact protein expression profiles as a snapshot of expressed proteins in a wide range of bacterial samples. Subsequent top-down proteomic analysis by LC-tandem MS allows identification of expressed serovar-specific proteins, resulting from nonsyn-onymous single-nucleotide polymorphisms (SNPs). Closely related, unsequenced or bacterial strains with newly acquired SNPs and plasmid proteins can be successfully differentiated by this multiplexed approach. [Pg.5]

See other pages where Single nucleotide polymorphism differential expression is mentioned: [Pg.382]    [Pg.391]    [Pg.52]    [Pg.73]    [Pg.667]    [Pg.780]    [Pg.6]    [Pg.23]    [Pg.230]    [Pg.90]    [Pg.32]    [Pg.49]    [Pg.482]    [Pg.65]    [Pg.31]   


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Single nucleotide polymorphism expression

Single nucleotide polymorphisms

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