Single and Multiple Collisions in CID

In beam-type analyzers, the collision event leading to ion activation can be considered in terms of the Lambert-Beer law, because the precursor ion beam flux [Mp]o is exponentially reduced when passing through a collision chamber of length I containing gas at target number density n 

In tandem-in-time experimoits as performed in trapping instruments a description in terms of rate constants and reaction times is more appropriate, which leads 

Note It has turned out that medium transmission is optimal for structure elucidation. Too strong reduction of the main beam favors ion losses due to scattering, charge exchange (M -H N M -H N ) or charge stripping processes (M -H N - + N ) instead of delivering additional structural information. 

---