Simvastatin in hyperlipidemia

In a study of the safety and efficacy of simvastatin in hyperlipidemia after renal transplantation in 15 patients, the Cmax and AUC of simvastatin were increased seven-fold by ciclosporin (260). In contrast, in 17 patients, tacrolimus had no effect. Although there were no complications, such as myopathy or rhabdomyolysis, creatine kinase activity must be monitored during co-administra-tion of simvastatin and ciclosporin. 

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See also in sourсe #XX -- [ , , , ]

See also in sourсe #XX -- [ ]

See also in sourсe #XX -- [ ]

See also in sourсe #XX -- [ , , , , ]

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