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Significance of Particle Retention

Most lung diseases are eaused by inhaled particulate compounds, such as cigarette smoke, viruses, baeteria, pollen, and occupational or environmental pollutants (i.e., toxic or radioactive aerosols). An increasing number of diagnostic and especially therapeutic aerosols (bronchodilators, anti-inflammatory drugs, antibiotics, [Pg.312]

Marcel Dekker, Inc. 270 Madison Avenue, New York, New York 10016 [Pg.312]

In addition to particle size and interfacial chemistry, shape also plays a role in particle wetting the sharper the edges of a particle, the less likely the particle will be wetted and displaced. Oliver et al. (120) have shown theoretically and experimentally, using a circular sapphire disk with a 90° edge, that sharp edges inhibit the spreading of liquids. [Pg.313]

The location of particles relative to the epithelial cells might determine their pathogenic or beneficial potential. The proximity of, for example, radioactive particles to sensitive structures, such as mitotic or stem cells, might influence the progeny of the airway lining and, by their location near the vasculature, systemic effects might be achieved (127). [Pg.314]


See other pages where Significance of Particle Retention is mentioned: [Pg.292]    [Pg.312]   


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