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Signal peptides SecB binding

SecA binds SecB and precursors, with both the mature region (Lill et al., 1990) and the signal peptide (Cunningham and Wickner, 1989) of the precursor participating in the interaction. SecA has a much higher... [Pg.154]

The overwhelming body of evidence demonstrates that SecB binds within the mature moiety of MBP, not the signal peptide. However, two predictions of this axiom have not been met (1) synthesis of mMBP should cause interference (it does not) and (2) mMBP synthesized in vitro should form detectable complexes with SecB (it does not). A resolution of this apparent paradox lies in the ability of the signal peptide to influence the rate of precursor folding and therefore indirectly affect SecB binding. [Pg.174]

See other pages where Signal peptides SecB binding is mentioned: [Pg.92]    [Pg.282]    [Pg.298]    [Pg.152]    [Pg.155]    [Pg.157]    [Pg.167]    [Pg.172]    [Pg.172]    [Pg.172]    [Pg.173]    [Pg.173]    [Pg.174]    [Pg.175]    [Pg.176]    [Pg.176]    [Pg.185]    [Pg.186]    [Pg.186]    [Pg.186]    [Pg.187]    [Pg.187]    [Pg.188]    [Pg.188]   
See also in sourсe #XX -- [ Pg.171 , Pg.172 ]



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