Sickle-cell anemia modifiers

Molecular medicine was a term used by two-time Nobel laureate in chemistry and peace Linus Pauling, Ph.D., in his landmark article on the mechanism of production of sickle cell anemia published in 1949.1 It defined a new perspective on the origin of disease based upon the recognition that specific mutations of the genes can create an altered "molecular environment" and therefore the modified physiological function associated with specific diseases. 

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