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Sialic acid pharmacokinetics

Based on these results, and with the aim of obtaining structurally simplified and pharmacokinetically improved MAG antagonists, a number of mimics of tetrasaccharide 67 were prepared and their affinity towards MAG tested in the fluorescent hapten inhibition assay [58] relative to 67 [70,71]. fii these studies, the Gal-P(l-3)-GaWAc core was simplified, the a(2-6)-linked sialic acid was replaced... [Pg.167]


See other pages where Sialic acid pharmacokinetics is mentioned: [Pg.148]    [Pg.159]    [Pg.388]    [Pg.445]    [Pg.118]    [Pg.834]    [Pg.2147]    [Pg.998]    [Pg.831]    [Pg.825]    [Pg.1132]    [Pg.780]    [Pg.141]    [Pg.295]    [Pg.299]    [Pg.1117]    [Pg.266]   
See also in sourсe #XX -- [ Pg.186 ]




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Acids pharmacokinetics

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