Shed-Acute-Phase-Antigen

T. cruzi fran -sialidase first named SARA ( Shed-Acute-Phase-Antigen ) and found in human serum in Chagas disease, is also unique from an immunological aspect, since it contains two immunologically distinct domains and seems to be a naturally chimeric protein having functionally independent enzymatic and antigenic domains [823]. (It is thus reminiscent of V. cholerae sialidase which consists of a catalytic domain and a non-catalytic sequence similar to those of legume lectins [768,791].)... 

---