Seven-membered cyclic-a-adduct

In such syntheses of -lactams a seven-membered cyclic a-adduct (133) is formed from (133) the 3-lactam system (134) results by transannular acyl transfer. As a consequence, the Ugi reaction has been used in numerous syntheses of 3-lactam antibiotics and related compounds." ... 

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See also in sourсe #XX -- [ , ]

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