Seven heuristics

When Osborn studied human creativity, he was not only interested in the development of a universal method of creative problem solving he was also searching for all physical and social factors contributing to increased 

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Note that, in this case, the design equations have seven terms (seven rate expressions), whereas in the formulation in part (a), design equations (d), (e), and (f), have only five terms. This illustrates that, by adopting the heuristic rule, we minimize the number of terms in the design equations. To solve the design equations, we have to express the rates of the individual reactions in terms of the dimensionless extents of the independent reactions, Z, Z5, and Ze. 

Kind, T. and Fiehn, O., Seven Golden Rules for heuristic filtering of molecular formulas obtained by accurate mass spectrometry, BMC Bioinform., 8, 105, 2007. 

Certain considerations of the skeleton define particular bonds as candidates for construction. A set of seven such skeletal criteria are listed here and discussed below. A number are obviously a part of current S5uithetic practice, often used intuitively. They deserve specific definition, however, as a basis for further systematic exploration, and more heuristic criteria of this kind are needed for the future 1 21. 

While all tree search techniques involve the expansion of nodes, one can proceed in a number of different ways. Systematic exploration at each level, even with six conformational states, is possible only for molecules consisting of six or seven conformational units. Beyond this size it is necessary to rely on some form of heuristic search which provides the means of finding a path between the root node and a goal node without generating all conformations at the intermediate levels. 

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