Semipolar ethyl esters

The solubilizing capacity of micelles and microemulsions prepared using the surfactant N,N-dimethyl-dodecylamine-N-oxide (C12AO), and containing either one of two semipolar ethyl ester oils (i.e., EH or EO) for the poorly water soluble, lipophilic steroidal drug, testosterone enanthate, has been determined recently (Barlow, D.J. Lawrence, M.J. Zuberi, T. Zuberi, S. Heenan, R.K. Personal communication, 2005). 

Gas-phase elimination reactions of ethyl esters of a- and /1-amino acids have been investigated in a static reaction system.20,21 The first step of decomposition of these esters is formation of the corresponding carboxylic acids and ethylene through a concerted six-membered cyclic transition state. The intermediate /1-amino acids decar-boxylate via a semipolar six-membered cyclic transition state. 

The differences have the sign and magnitude which is associated with a mixed bond, and this confirms the structure assigned on p. 52. The ethyl ester of phenylmethylphosphinic acid had a paraehor of 420-5 that calculated on the assumption of an ordinary double bond was 442-1, while on the assumption of a mixed or semipolar bond it was 417-3. The structure was therefore given as... 

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