Self-Assembly into the Most Enantioselective Catalyst

4 Self-Assembly into the Most Enantioselective Catalyst 

The role of multicomponent ligand assembly into a highly enantioselective catalyst is shown in the enantioselective catalysis for the carbonyl-ene reaction (Table 8.9). The catalyst is prepared from an achiral precatalyst, Ti(0 Pr)4 and a combination of BINOL with various chiral diols such as TADDOL and 5-Cl-BIPOL in a molar ratio of 1 1 1 (10mol% with respect to the olefin and glyoxylate) in 

5 Asymmetric Activation of Chiraiiy Fiexibie (Tropos) Catalysts 

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