Selenazoles, 1,3-selenazolidines and 1,3-tellurazoles

A series of 2-amino-1,3-selenazole-5-carbonitriles 290 are readily prepared from selenazadienes 287 upon treatment with chloroacetonitrile in the presence of triethylamine 05JHC831 . Similarly, reaction of selenoazadiene 291 with chloroacetyl chloride generates acyl chloride 292, which is trapped with various amines to yield the corresponding amides 293 

Several 2-imino-l,3-selenazolidine derivatives 295 and 297 are prepared in the same fashion as their 1,3-thiazolidine counterparts as described in section 5.5.2.3 from the corresponding (9-methanesulfonyl P-amino alcohol hydrochlorides 294 and 296, respectively, using potassium selenocyanate 05TL233 . 

---