Selective Deprotection of Alcoholic and Phenolic TBDMS Ethers

Selective Deprotection of Alcoholic and Phenolic TBDMS Ethers 14) 

Under carefully controlled conditions, TBAF and aqueous HF selectively deprotect phenolic and alcoholic silyl ethers respectively. An excess of either reagent will, of course, ultimately result in complete deprotection. 

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