Sedation antipsychotic agents causing

Hyoscine and sedating antihistamines increase the effects of other drugs that cause sedation or have antimuscarinic actions, including many antidepressants and antipsychotic agents. 

Which of the following agents possesses pharmacological actions characterized by high antipsychotic potency, high potential for extrapyramidal toxicity, and a low likelihood of causing sedation ... 

Chlorpromazine produces a tranquihty characterized by a detached serenity without depression of mental faculties or clouding of consciousness. It depresses the CNS selectively by reducing input directed to the reticular formation through collaterals arriving from the sensory pathways. Chlorpromazine-induced sedation differs from that caused by barbiturates in that the patient can be easily aroused. In practice, the more sedative neuroleptics are often prescribed for agitated, overactive patients, and the less sedative agents are used for apathetic, withdrawn patients. However, sedation is not necessary for its antipsychotic property for two reasons (1) tolerance develops to the sedative effects, and (2) fluphenazine, prochlorperazine, and trifluoperazine are excellent neuroleptics that lack pronounced sedative effects. 

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