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Secondary chiral solvent-free

Several recent articles describe the ring-opening of chiral epoxides under microwave irradiation conditions (see also Scheme 6.103). In the context of the preparation of novel /32-adrenoceptor agonists related to formoterol and salmeterol, Fairhurst and a team from Novartis have described the synthesis of chiral ethanolamines by solvent-free microwave-assisted ring-opening of a suitable chiral epoxide precursor with secondary benzylated amines (Scheme 6.129) [262]. At 110 °C, the reaction occurred... [Pg.193]

See other pages where Secondary chiral solvent-free is mentioned: [Pg.857]    [Pg.458]    [Pg.202]    [Pg.214]    [Pg.645]    [Pg.356]    [Pg.504]    [Pg.504]    [Pg.228]    [Pg.21]    [Pg.1139]    [Pg.29]    [Pg.163]    [Pg.130]    [Pg.212]    [Pg.376]   
See also in sourсe #XX -- [ Pg.157 ]



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Free secondary

Secondary chiral

Secondary solvent

Solvent-free

Solvents chiral

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