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Fig. 19.1. Learning acquisition in the spatial reference memory version of a water maze test of mixed background C3B6 mice in two different animal colonies. Mice in the colony A were kept in a quiet room with appropriate for behavioral experiments husbandry practices, while the colony B had increased noise level and sub-optimal for behavioral studies conditions. The mice trained in the colony A showed a significant improvement in finding a hidden platform location during training (their search path was on average about 5 m shorter at the end of training as compared to at the beginning of training). On the other hand, the mice in colony B showed no improvement (the rate of improvement between day 1 and day 5 was about 1 m). See text for further details. Fig. 19.1. Learning acquisition in the spatial reference memory version of a water maze test of mixed background C3B6 mice in two different animal colonies. Mice in the colony A were kept in a quiet room with appropriate for behavioral experiments husbandry practices, while the colony B had increased noise level and sub-optimal for behavioral studies conditions. The mice trained in the colony A showed a significant improvement in finding a hidden platform location during training (their search path was on average about 5 m shorter at the end of training as compared to at the beginning of training). On the other hand, the mice in colony B showed no improvement (the rate of improvement between day 1 and day 5 was about 1 m). See text for further details.

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