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Scrapie protein-only hypothesis

The protein-only hypothesis indicates that the scrapie form of the prion protein can promote the conversion of the cellular form. This leads to the conclusion that prions themselves can act as chaperones (Liautard, 1991). Thermokinetic analysis of protein folding shows that a misfolded chaperone gives rise to new misfolded chaperones, which fit very well to the protein-only hypothesis in which PrP triggers the formation of PrP. ... [Pg.244]

See other pages where Scrapie protein-only hypothesis is mentioned: [Pg.799]    [Pg.571]    [Pg.404]    [Pg.404]    [Pg.170]    [Pg.55]    [Pg.83]    [Pg.275]    [Pg.280]    [Pg.299]    [Pg.532]    [Pg.535]    [Pg.537]    [Pg.52]    [Pg.23]    [Pg.6]    [Pg.315]    [Pg.205]   
See also in sourсe #XX -- [ Pg.83 , Pg.96 , Pg.248 , Pg.275 ]



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Protein only hypothesis

Scrapie

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