Schrock-Hoveyda catalyst

Figure 16.13. Schrock-Hoveyda catalyst for asymmetric metathesis...

The molybdenum complex of 1,1 -biphenyl-2,2 -diol-based ligand (BIPHEN) possessing an axial element of chirality proved to be an efficient catalyst in various modes of enantioselective olefin metathesis (71). (The catalytic precursor is known as the Schrock-Hoveyda catalyst.)... 

Fig. 16. Chiral molybdenum containing (Schrock-Hoveyda) catalyst.

The molybdenum(VI) complex with BIPHEN (Schrock-Hoveyda catalyst) has been widely used as an enantioselective olefin metathesis catalyst for a variety of substrates (145). Recently, the synthesis of a tetrahydrocannabiol derivative in molybdenum-catalyzed asymmetric allylic alkylation by using Trost-ligands is carried out. Enhanced regio-, enantio-, and diastereoselectivities relative to the palladium ones have been observed (146). 

Hayano, S. Kurakata, H. Uchida, D. Sakamoto, M. Kishi, N. Matsumoto, H. Tsunogae, Y. Igarashi, I. Stereospecific ring-opening metathesis polymerization of ewrfo-dicyclopentadiene by Schrock-Hoveyda catalyst and novel Mo- and W-based complexes. Development of crystalline hydrogenated poly(e rfo-dicyclopentadiene). Chem. Lett. 2003, 32, 670-671. 

---